DSP seminar: October 16, 1997 Bayesian Models in Tomography and Imaging Charles A. Bouman Purdue University School of Electrical and Computer Engineering West Lafayette IN 47907 Many problems in image processing require the recovery of an unknown image from noisy or incomplete information. For example, tomographic reconstruction requires that an unknown image (or volume) be estimated from a set of projection measurements. Often, these measurements may be noisy or incomplete, so the exact solution can not be obtained through a simple inverse operation. For such ill-posed inverse problems, it is very useful to incorporate an image model into the inversion process since the model can capture essential characteristics such as smooth regions and edges in images. In particular, Bayesian statistical techniques form an elegant framework for incorporating such prior knowledge about image behavior through an assumed prior image distribution. This talk focuses on some key aspects of good prior image models and illustrates their value in the context of two applications: tomography and segmentation. In particular, we argue that a good model should be: 1) Robust and/or adaptable to image behavior 2) Able to model both global and local image characteristics 3) Computationally tractable We first briefly review methods for applying the Bayesian estimation framework to tomographic reconstruction problems and show how Markov random fields (MRF) can be used to simply model image cross-sections. We discuss how proper choice of the MRF model can improve robustness, and how the model can be automatically adapted through the use of parameter estimation methods based on the expectation maximization EM algorithm. We next introduce a class of prior models based on a multiscale structure which are better suited to modeling more global image characteristics, and we present examples of their use in both tomography and segmentation applications.